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EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential

https://doi.org/10.1038/s41590-020-0595-7

Marta Derecka , Josip Stefan Herman, Pierre Cauchy, Senthilkumar Ramamoorthy, Ekaterina Lupar, Dominic Grün, Rudolf Grosschedl

Identified clusters after k-medoids clustering & used sorting gates

(Loading of data takes app. 30s)

Compare one cluster against all the other clusters

Choose a cluster

mean.ncl = mean expression of gene not in cluster

mean.cl = mean expression of gene in cluster

fc = fold change compared to all other clusters

pv = p-value

padj = adjusted p-value

Set p-value threshhold

Set adjusted p-value threshhold

Plot gene expression in tSNE-Map

Enter a genesymbol

Compare gene expression of two clusters

Choose cluster 1

Choose cluster 2

Set p-value threshhold

Set adjusted p-value threshhold

Choose number of top genes to display

MA Plot

Interactive MA Plot

Imprint
Privacy Notice

Shiny app contact: Josip S. Herman

EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential

https://doi.org/10.1038/s41590-020-0595-7

Marta Derecka , Josip Stefan Herman, Pierre Cauchy, Senthilkumar Ramamoorthy, Ekaterina Lupar, Dominic Grün, Rudolf Grosschedl

Identified clusters after k-medoids clustering & used sorting gates

(Loading of data takes app. 30s)

Compare one cluster against all the other clusters

Choose a cluster

mean.ncl = mean expression of gene not in cluster

mean.cl = mean expression of gene in cluster

fc = fold change compared to all other clusters

pv = p-value

padj = adjusted p-value

Set p-value threshhold

Set adjusted p-value threshhold

Plot gene expression in tSNE-Map

Enter a genesymbol

Compare gene expression of two clusters

Choose cluster 1

Choose cluster 2

Set p-value threshhold

Set adjusted p-value threshhold

Choose number of top genes to display

MA Plot

Interactive MA Plot

Imprint
Privacy Notice

Shiny app contact: Josip S. Herman

EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential

https://doi.org/10.1038/s41590-020-0595-7

Marta Derecka , Josip Stefan Herman, Pierre Cauchy, Senthilkumar Ramamoorthy, Ekaterina Lupar, Dominic Grün, Rudolf Grosschedl

Identified clusters after k-medoids clustering & used sorting gates

(Loading of data takes app. 30s)

Compare one cluster against all the other clusters

Choose a cluster

mean.ncl = mean expression of gene not in cluster

mean.cl = mean expression of gene in cluster

fc = fold change compared to all other clusters

pv = p-value

padj = adjusted p-value

Set p-value threshhold

Set adjusted p-value threshhold

Plot gene expression in tSNE-Map

Enter a genesymbol

Compare gene expression of two clusters

Choose cluster 1

Choose cluster 2

Set p-value threshhold

Set adjusted p-value threshhold

Choose number of top genes to display

MA Plot

Interactive MA Plot

Imprint
Privacy Notice

Shiny app contact: Josip S. Herman

EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential

https://doi.org/10.1038/s41590-020-0595-7

Marta Derecka , Josip Stefan Herman, Pierre Cauchy, Senthilkumar Ramamoorthy, Ekaterina Lupar, Dominic Grün, Rudolf Grosschedl

Identified clusters after k-medoids clustering & used sorting gates

(Loading of data takes app. 30s)

Compare one cluster against all the other clusters

Choose a cluster

mean.ncl = mean expression of gene not in cluster

mean.cl = mean expression of gene in cluster

fc = fold change compared to all other clusters

pv = p-value

padj = adjusted p-value

Set p-value threshhold

Set adjusted p-value threshhold

Plot gene expression in tSNE-Map

Enter a genesymbol

Compare gene expression of two clusters

Choose cluster 1

Choose cluster 2

Set p-value threshhold

Set adjusted p-value threshhold

Choose number of top genes to display